IFUM

Jointly estimates absolute folding stability (DeltaG) and equilibrium structural ensembles.

Key Info

• URL: https://github.com/HParklab/IFUM
• Category: Protein Structure
• API: Yes
• Free: Free
• ACMG Relevance: PP3
• Link Status: Unchecked

Why It Matters

Highly robust to sequence insertions and deletions, enhancing the prediction of mutational effects on thermodynamic stability.

STRC Research Usage

Not yet tested on E1659A.

Next Steps

• Verify URL accessibility
• Test with STRC E1659A variant if applicable
• Document specific results

Connections

• STRC Variant c.4976A>C — Misha [see-also]
• STRC Gene [about]