EVcouplings

Predicts 3D structural conformations and mutation fitness landscapes from evolutionary sequence covariation.

What it does

Moves significantly beyond single-site conservation by modeling how a variant at one position dictates permissible changes at distant residues.

How to use

See https://evcouplings.org/ for documentation and access.

STRC usage

Documented. Requires local installation or specialized access for STRC E1659A testing.

Connections

• STRC Variant c.4976A>C — Misha [see-also]
• STRC Gene [about]
• [part-of] Tools index